plos.org

80 articles in the TruthFoundry index. Each links out to the original.

• LAKANA Mali trial finds twice-yearly azithromycin does not raise antimicrobial resistance · LAKANA trial sub-study assesses azithromycin antimicrobial resistance outcomes in Mali.
• Caregiver mental health proposed for African paediatric HIV/TB care · Researchers advocate integrating caregiver mental health into African paediatric HIV and TB care.
• Pneumococcal Vaccination Campaigns Show Promise in Humanitarian Settings · A modelling study finds single-dose pneumococcal vaccination campaigns can significantly reduce disease in crisis-affected populations.
• Global ROI of COVID-19 Vaccines in First Year of Vaccination Program · A study finds that global investment in COVID-19 vaccines delivered a high return-on-investment in the first year of the vaccination program.
• Study identifies weight loss metabolomic signature for BMI linked diseases · Research finds 242 weight loss metabolites with disease-specific BMI disease associations
• Multiregional statin study links lower cholesterol to reduced cardiovascular events · Large cohort study finds lower post-statin cholesterol reduces cardiovascular event risk.
• Modeling study finds standard influenza antiviral stockpiles fail severe pandemics · Research shows traditional 25% population antiviral stockpiles cannot prevent healthcare system collapse in severe pandemics.
• Ioannidis outlines validity threats in large biomedical dataset research · Researchers identify four core validity risks for large biomedical dataset studies.
• Finnish study finds childhood type 1 diabetes rates fell post COVID lockdown · Finnish research finds childhood type 1 diabetes incidence dropped 15% after COVID lockdowns.
• Phase 4 trial compares IPC and UTRC rabies vaccine regimens in India · Randomised trial finds 1-week IPC rabies regimen not equivalent to 1-month UTRC regimen.
• Novel RAS inhibitor daraxonrasib improves pancreatic cancer survival outcomes · Daraxonrasib doubled overall survival in metastatic pancreatic cancer phase 3 trials.
• Challenges and Recommendations for Implementing Oncology Clinical Practice Guidelines in China · China's oncology clinical practice guidelines face systemic implementation challenges despite growth in quantity and quality.
• California power shutoffs linked to increased respiratory healthcare visits · Wildfire prevention power shutoffs raise acute respiratory healthcare utilization in California.
• Systematic review finds non-pharmacological low back pain treatments cost-effective · Systematic review finds non-surgical non-drug low back pain interventions deliver better value than usual care.
• Study Estimates AMR Deaths Averted By Reduced Global Antibiotic Use · 10% global antibiotic use reduction could prevent 38,000 annual AMR deaths per research.
• Breast Cancer Treatment De-Escalation Reduces Harm Safely · PLOS Medicine editorial advocates for reduced breast cancer treatment for eligible patients.
• Study compares home vs facility care for mild diphtheria in Nigeria epidemic · Retrospective cohort study evaluates home care for mild diphtheria during Kano State epidemic.
• Cardiac Screening For Youth Reviewed For Sudden Cardiac Death Prevention · Researchers analyse global cardiac screening practices for preventing sudden cardiac death in young people.
• Guidance for Defining Outcomes in Clinical Trials · Researchers develop a framework to ensure complete and consistent outcome definitions in clinical trials.
• Global review links violence to worse HIV outcomes for female sex workers · Meta-analysis finds violence correlates with higher HIV risk and poorer treatment outcomes for female sex workers.
• Standard cardiovascular risk models fail to identify many at-risk patients · Conventional cardiovascular risk equations miss events in people classified as low risk.
• WHO 2026 doxy-PEP guidelines require monitoring for antimicrobial resistance risks · Researchers outline monitoring requirements and review triggers for WHO doxy-PEP STI prophylaxis guidelines.
• Natural Immunity Biases Shigella Vaccine Efficacy Trial Estimates, Study Finds · Simulation modeling demonstrates natural Shigella immunity distorts vaccine efficacy trial results.
• CBI-M Framework for Traumatic Brain Injury Evaluation Using Large Cohort Studies · CBI-M framework shows strong performance in characterizing traumatic brain injury across diagnosis, care pathways, and outcomes.
• Plasma Proteomic Signatures for Cardiovascular Risk Stratification in Subclinical Atherosclerosis · A study identifies plasma proteomic signatures that improve cardiovascular risk stratification for subclinical atherosclerosis.
• Wales study links congenital anomalies, deprivation to educational attainment · Welsh population study finds deprivation impacts school attainment more than congenital anomalies.
• NIH-AARP cohort finds no total ultra-processed food colorectal cancer link · Large US cohort finds total ultra-processed food intake not associated with colorectal cancer risk.
• Multi-model study evaluates typhoid conjugate vaccine schedule effectiveness · WHO commissioned analysis assesses optimal typhoid conjugate vaccine schedules across global settings.
• South Korean cohort links prenatal opioids to increased child hospital admissions · Nationwide South Korean study finds prenatal opioid exposure raises child hospital admission risk.
• Amlodipine Shows Better Outcomes Than Nifedipine in Stroke Patients, Study Finds · Amlodipine is associated with improved functional recovery in ischemic stroke or TIA patients compared to nifedipine, according to a 5-year follow-up study.