Nature

42 articles in the TruthFoundry index. Each links out to the original.

• Study links brain DNA methylation, APOE to Alzheimer's neuropathology · Large postmortem cohort analyzes DNA methylation and APOE in Alzheimer's pathology
• Single-cell analysis maps endothelial cell aging transcriptional hallmarks · Researchers built the HAECA atlas of human endothelial cell aging across 12 organs.
• Naive T cell decline reduces cancer immunity in middle-aged male mice study finds · Research links naive CD8+ T cell loss to impaired cancer immunity in middle-aged male mice.
• Type 2 immunity proposed as gerotherapeutic target for aging inflammation · Researchers propose Type 2 immunity erosion drives inflammaging during biological aging.
• Senescent naive B cells contribute to rheumatoid arthritis progression · Research identifies senescent-like B cells as drivers of clinical rheumatoid arthritis onset.
• Chaperone-mediated autophagy declines with aging, driving senescence · Research shows declining chaperone-mediated autophagy increases senescent cell burden and tissue dysfunction.
• Study links sex-biased T cell decline to impaired middle age cancer immunity · Male mice exhibit faster naive CD8+ T cell loss reducing cancer immune response by middle age
• Mouse study finds oocyte heterogeneity preserves female fertility lifespan · Research identifies variable activated oocyte lifespan regulated by FURIN in female mice.
• Correction: Data errors in study on RAB-10 and intestinal barrier integrity · Authors correct data transfer errors in figures and source files regarding RAB-10 efficacy.
• Suppressing PLA2G7 in neural stem cells improves cognition in aging mice · Study finds inhibiting PLA2G7 restores brain circuit function and cognition in aged mice
• Transcriptomic Screen Identifies SRSF1 as Aging Regulator · A transcriptomic reprogramming screen identifies SRSF1 as a key regulator of aging.
• Nature Aging Corrects Data and Statistical Annotations in Primate Aging Study · Nature Aging publishes corrections for data mix-ups and statistical significance errors in a study on intestinal aging.
• Longitudinal multiomics reveals personalized aging trajectories in TwinsUK cohort · Researchers used longitudinal multiomics data from 335 women to map personalized aging trajectories.
• Peripheral dendritic cells drive tau neurodegeneration via CD8+ T cell priming · Research identifies immune mechanism driving tau-related neurodegeneration in mouse models.
• Cross-sectional and longitudinal designs yield divergent genetic age effects · Analysis of UK Biobank data reveals significant discrepancies between cross-sectional and longitudinal estimates of age-varying genetic effects.
• Lipid Chain Elongation Identified as Conserved Hallmark of Aging · Researchers identify lipid acyl chain elongation as a conserved hallmark of aging across tissues and species.
• Longer lipids in aging organisms constrain lifespan · Research indicates that longer lipid chains accumulate with age and limit lifespan across multiple species.
• Age-related CMA decline impairs macrophage clearance of senescent cells · Reduced chaperone-mediated autophagy with age blocks immune removal of senescent cells.
• Study Correction: Multilingualism Linked to Slower Aging in 27 European Countries · Nature Aging corrects an error excluding Slovakia, confirming multilingualism reduces accelerated aging risk.
• Correction: Study removed flawed somatic mutation rate comparison · Authors of a Nature Aging study removed a flawed comparison of somatic mutation rates due to unaccounted in vitro expansion.
• Study Identifies Oral Bacteria as Key to Human Aging Protection · Researchers identified Neisseria flavescens as a central geroprotective oral commensal in humans using multi-omics profiling.
• Cross-species kidney atlas reveals epithelial aging in disease · A new cross-species kidney atlas identifies tubular epithelia as the primary driver of disease-associated epigenetic aging.
• 6th TimePie Longevity Forum Advances Aging Biomarker Research · 2025 TimePie Longevity Forum in Shanghai gathered global aging research experts.
• Author Correction Issued For APOE Senescence Research Paper · An author correction was published for a research paper on APOE and senescence.
• Exercise Enhances Aged Chondrocyte Health via MicroRNA-29-Rich Extracellular Vesicles · Research identifies how exercise-derived extracellular vesicles containing microRNA-29 protect aged cartilage cells.
• RamanOmics method reveals biochemical landscape of cellular senescence · Zhang et al present RamanOmics, a multimodal tool for profiling senescent cell chemistry.
• RamanOmics Platform Maps Biochemical and Genetic Aging in Tissues · Researchers developed RamanOmics to link vibrational biochemical states with gene expression in aging mouse tissues.
• Cytotoxic CD4+ T Cells Drive Age-Related Myelopoiesis via CCL5–CCR5 Axis · Cytotoxic CD4+ T cells promote age-associated myelopoiesis through the CCL5–CCR5 axis in mice.
• Nature Aging Corrects Figure Error in Ovarian Aging Study · Nature Aging issues a publisher correction regarding a typesetting error in a study on physical activity and ovarian aging.
• Nature Aging publishes correction for ovarian reserve research article · Nature Aging corrected an author surname error in a published ovarian aging study.